Main Menu Top Menu

Xanthorrhizol: a review of its pharmacological activities and anticancer properties

Xanthorrhizol: a review of its pharmacological activities and anticancer properties

Oon SF1, Nallappan M1, Tee TT2, Shohaimi S1, Kassim NK3, Sa’ariwijaya MS4, Cheah YH2.

Cancer Cell Int. 2015 Oct 21;15:100

Abstract
Xanthorrhizol (XNT) is a bisabolane-type sesquiterpenoid compound extracted from Curcuma xanthorrhiza Roxb. It has been well established to possess a variety of biological activities such as anticancer, antimicrobial, anti-inflammatory, antioxidant, antihyperglycemic, antihypertensive, antiplatelet, nephroprotective, hepatoprotective, estrogenic and anti-estrogenic effects. Since many synthetic drugs possess toxic side effects and are unable to support the increasing prevalence of disease, there is significant interest in developing natural product as new therapeutics. XNT is a very potent natural bioactive compound that could fulfil the current need for new drug discovery. Despite its importance, a comprehensive review of XNT’s pharmacological activities has not been published in the scientific literature to date. Here, the present review aims to summarize the available information in this area, focus on its anticancer properties and indicate the current status of the research. This helps to facilitate the understanding of XNT’s pharmacological role in drug discovery, thus suggesting areas where further research is required.
KEYWORDS:
Anticancer; Curcuma xanthorrhiza Roxb.; Pharmacological; Xanthorrhizol

Full paper: 

This entry was posted in Curcumin, Turmeric. Bookmark the permalink.

Leave a Reply

Your email address will not be published. Required fields are marked *